help button home button Endocrine Society JCEM JCEM Call for Nominations for EIC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Keye, W. R.
Right arrow Articles by Jaffe, R. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Keye, W. R., Jr
Right arrow Articles by Jaffe, R. B.

Journal of Clinical Endocrinology & Metabolism, Vol 42, 1133-1138, Copyright © 1976 by Endocrine Society

ARTICLES

Changing patterns of FSH and LH response to gonadotropin-releasing hormone in the puerperium

WR Keye Jr and RB Jaffe

Gonadotropin responses to synthetic gonadotropin-releasing hormone (GnRH or LRF), as well as basal concentrations of gonadogropins, estradiol, and prolactin, were determined at weekly intervals during the first eight weeks post partum in seven non-nursing, non-steroid- treated women. The results were compared with those of a group of eleven women studied on the second day of the menstrual cycle. In the postpartum group, baseline concentrations of LH and FSH similar to those seen in the early follicular phase of the menstrual cycle occurred by the third week post partum. In response to an iv bolus of 100 mug GnRH, elevations of serum LH: 1) occurred as early as the second postpartum week; 2) were less than those of women during the early follicular phase until the fourth postpartum week; and 3) were exaggerated (when compared with those ob subjects in the early follicular phase) during the fifth through the eighth week post partum. Similarly, the FSH responses to GnRH in the puerperium were similar to those of the subjects during the early follicular phase by the third week post partum, and were exaggerated during the second month post partum. These studies demonstrate that human pregnancy is followed by a period of relative pituitary refractoriness followed by one of increased responsiveness to GnRH.


This article has been cited by other articles:


Home page
 J EndocrinolHome page
H. L Henderson, J. Townsend, and D. J Tortonese
Direct effects of prolactin and dopamine on the gonadotroph response to GnRH
J. Endocrinol., May 1, 2008; 197(2): 343 - 350.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
P. Villaseca, C. Campino, E. Oestreicher, D. Mayerson, M. Seron-Ferre, and E. Arteaga
Bilateral oophorectomy in a pregnant woman: hormonal profile from late gestation to post-partum: Case report
Hum. Reprod., February 1, 2005; 20(2): 397 - 401.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1976 by The Endocrine Society