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AND β GLYCOPROTEIN HORMONE SUBUNITS (hLH, hFSH, hCG) IN THE SERUM AND PITUITARY OF THE HUMAN FETUS¹

DEPARTMENT OF PEDIATRICS, UNIVERSITY OF CALIFORNIA SAN FRANCISCO SAN FRANCISCO, CALIFORNIA 94143

Utilizing specific radioimmunoassay and gel chromatographic separation methods, the concentration of glycoprotein hormone subunit and the β subunit of hCG, hLH, and hFSH was determined. The glycoprotein hormone subunit is present throughout gestation in the serum and pituitary of the human fetus; little or no β subunit is detectable. No sex difference in the levels of glycoprotein hormone subunit is apparent in contrast to that of intact LH and FSH.

¹ Submitted 1/7/76

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