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Journal of Clinical Endocrinology & Metabolism, Vol 42, 864-868, Copyright © 1976 by Endocrine Society

ARTICLES

Body composition in Cushing's disease

SW Lamberts and JC Birkenhager

Lean body mass and body fat mass were estimated in 12 patients with Cushing's disease before treatment, in 5 of these after correction of the adrenal hyperfunction, and in 23 patients with simple obesity. The methods used, whole-body counting of 40K and tritiated water dilution, may in Cushing's disease over- and underestimate, respectively, the body fat mass and may therefore be considered to give upper and lower limits of that entity. By a comparison with the results in simple obesity, we conclude that the total body fat mass generally is increased in patients with Cushing's disease.


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