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Journal of Clinical Endocrinology & Metabolism, Vol 42, 544-550, Copyright © 1976 by Endocrine Society

ARTICLES

Hypersecretion of LH and FSH by a pituitary adenoma

PJ Snyder and FH Sterling

A 51-year-old man who had a pituitary adenoma that appeared to be hypersecreting LH and FSH is described. Not only were serum LH and FSH concentrations above the normal ranges, but the serum concentrations of testosterone, free testosterone, and dihydrotestosterone were also above normal. Serum LH and FSH concentration increased in response to synthetic thyrotropin-releasing hormone as well as to synthetic gonadotropin-releasing hormone. The elevated hormone concentrations decreased following an initial partial hypophysectomy and decreased further following repeat hypophysectomy.




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Copyright © 1976 by The Endocrine Society