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Journal of Clinical Endocrinology & Metabolism, Vol 42, 464-467, Copyright © 1976 by Endocrine Society

ARTICLES

Androsterone sulfate concentrations in plasma in hypo- and hyperthyroidism

RS Rosenfeld, J Kream and L Hellman

Androsterone sulfate concentrations have been measured in the plasma of 16 hypothyroid women and 14 hyperthyroid women by a gas-liquid chromatographic technique and in 23 hypothyroid and 18 hyperthyroid women by radioimmunoassay. In obth studies androsterone sulfate concentrations were significantly higher in the hyperthyroid groups. In one hypothyroid subject, blood was obtained at 20-minute intervals over 24 hours before and after the administration of triiodothyronine; plasma androsterone sulfate, initially 25 mug per dl, increased three- fold as a consequence of treatment.




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Copyright © 1976 by The Endocrine Society