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Journal of Clinical Endocrinology & Metabolism, Vol 42, 28-32, Copyright © 1976 by Endocrine Society

ARTICLES

Depressed plasma FFA turnover rate in Cushing's syndrome

JC Birkenhager, HA Timmermans and SW Lamberts

The turnover rate of plasma FFA measured by constant infusion of albumin-complexed labeled palmitate in a group of 16 patients with Cushing's syndrome was significantly lower than in a group of 6 controls. Seven patients reexamined after correction of the hypercortisolism showed a normalization of the plasma FFA turnover rate. By contrast, 7 patients with simple obesity had a normal or increased plasma FFA turnover rate depending on the way this parameter is expressed.


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D. P Macfarlane, S. Forbes, and B. R Walker
Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome
J. Endocrinol., May 1, 2008; 197(2): 189 - 204.
[Abstract] [Full Text] [PDF]


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