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Journal of Clinical Endocrinology & Metabolism, Vol 41, 985-988, Copyright © 1975 by Endocrine Society

ARTICLES

Dopamine infusion acutely inhibits the TSH and prolactin response to TRH

GS Besses, GN Burrow, SW Spaulding and RK Donabedian

Ten normal males were given 100 mug TRH, and blood samples obtained for serum TSH and serum prolactin. After a period of at least one week, the TRH test was repeated while the patients were receiving a dopamine infusion. Both the TSH and prolactin response to TRH were inhibited by dopamine. Dopaminergic neurons may act through the pituitary-portal system to play a role in the regulation of TSH and prolactin secretion.


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[Abstract] [Full Text] [PDF]


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