Iodine-Induced Thyrotoxicosis in Apparently Normal Thyroid Glands
J. C. SAVOIE,
J. P. MASSIN,
P. THOMOPOULOS and
F. LEGER
Department of Nuclear Medicine, Hôpital La Pitié Paris 13, France
Reprints: Dr. J. C. Savoie, Service Central de Médecine Nucléaire, Hôpital La Pitié, 75634 Paris, France.
Although iodine-induced thyrotoxicosis was reported to occurin patients with obvious underlying thyroid disorders, it isnot known to occur in patients with apparently normal thyroidglands. From ten such cases evidence is presented that thyrotoxicosis:a) appeared during treatments by iodide or organic-iodine-containingdrugs, in the absence of any past history of thyroid disorder;b) was accompanied by almost undetectable radioiodine uptakewhich nevertheless could be activated by TSH; c) subsided spontaneouslywithin a few weeks or months after stopping the high intakeof iodine; d) and left, after a period of hypothyroidism, anapparently normal thyroid gland which had resumed normal size,function, uptake, and suppressibility.
Supported by the Institut National de la Santé et dela Recherche Médicale C.R.L., No. 72.2.090.7.
Received June 14, 1974.
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