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Journal of Clinical Endocrinology & Metabolism, Vol 41, 186-188, Copyright © 1975 by Endocrine Society

ARTICLES

Plasma aldosterone response to low dose ACTH stimulation

MG Nicholls, EA Espiner and RA Donald

The brief (60-min) infusion of a small amount (1.25 mug) of ACTH into 7 normal subjects on an unrestricted sodium intake resulted in a vigorous plasma aldosterone response in each case. This finding suggests that physiologic fluctuations in ACTH may significantly alter aldosterone secretion in normal man.


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