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Journal of Clinical Endocrinology & Metabolism Vol. 41, No. 1 164-167
doi:10.1210/jcem-41-1-164
Copyright © 1975 by the Endocrine Society.
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Elevated Prostaglandins and Suppressed Parathyroid Hormone Associated with Hypercalcemia and Renal Cell Carcinoma

R. PAUL ROBERTSON, DAVID J. BAYLINK, JOHN J. MARINI and H. WILLIAM ADKISON

Department of Medicine, University of Washington, and Veterans Administration Hospital Seattle Washington

Reprint requests should be addressed to Dr.Robertson at the Veterans Administration Hospital, 4435 Beacon Avenue South, Seattle, Washington 98108.

A patient with renal cell carcinoma and hypercalcemia was found to have suppressed serum parathyroid hormone levels but striking elevations of immunoreactive prostaglandins in plasma and metastatic tissue. It was hypothesized that prostaglandins may have either played a role in the hypercalcemia or were part of a counterregulatory event.

Received September 23, 1974.




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[Abstract] [PDF]




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Copyright © 1975 by The Endocrine Society