help button home button Endocrine Society JCEM JCEM Call for Nominations for EIC
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Submit a related Letter to the Editor
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Moshang, T.
Right arrow Articles by Snyder, P. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Moshang, T., Jr
Right arrow Articles by Snyder, P. J.

Journal of Clinical Endocrinology & Metabolism, Vol 40, 470-473, Copyright © 1975 by Endocrine Society

ARTICLES

Low serum triiodothyronine in patients with anorexia nervosa

T Moshang Jr, JS Parks, L Baker, V Vaidya, RD Utiger, AM Bongiovanni and PJ Snyder

Patients with anorexia nervosa can demonstrate clinical and/or laboratory findings suggestive of reduced thyroid hormone secretion. In this study, the thyroxine (T4) and triiodothyronine (T3) serum concentrations, and thyrotropin (TSH) response to intravenous administration of thyrotropin releasing hormone (TRH) were determined in 6 patients (aged 9 to 15 yr) with anorexia nervosa and the results compared to those found in a group of 15 normal subjects. The mean basal TSH concentration and mean maximum increase in TSH after TRH were comparable to those in the normal subjects. The mean T4 concentration (7.2 mug/100 ml) in the anorexia nerovsa group was slightly but significantly lower than in the normal group (9.5 mug/100 ml). Five of the 6 patients had serum T3 concentrations below the lower limits of normal and the mean T3 concentrations (49.7 ng/100 ml) was significantly lower than in the normal group (106 ng/100 ml). The extremely low serum levels of T3 in these patients with anorexia nervosa suggest that peripheral conversion of T4 to T3 is impaired during chronic starvation.


This article has been cited by other articles:


Home page
 PediatricsHome page
N. D. Kellogg and J. L. Lukefahr
Criminally Prosecuted Cases of Child Starvation
Pediatrics, December 1, 2005; 116(6): 1309 - 1316.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
A. L. D. Riis, T. K. Hansen, N. Moller, J. Weeke, and J. O. L. Jorgensen
Hyperthyroidism Is Associated with Suppressed Circulating Ghrelin Levels
J. Clin. Endocrinol. Metab., February 1, 2003; 88(2): 853 - 857.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
K. F. M. Joosten, E. D. de Kleijn, M. Westerterp, M. de Hoog, F. C. v Eijck, W. C. J. Hop, E. vd Voort, J. A. Hazelzet, and A. C. S. Hokken-Koelega
Endocrine and Metabolic Responses in Children with Meningoccocal Sepsis: Striking Differences between Survivors and Nonsurvivors
J. Clin. Endocrinol. Metab., October 1, 2000; 85(10): 3746 - 3753.
[Abstract] [Full Text]

Home page
 NEJMHome page
A. E. Becker, S. K. Grinspoon, A. Klibanski, and D. B. Herzog
Eating Disorders
N. Engl. J. Med., April 8, 1999; 340(14): 1092 - 1098.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Endocrinology Endocrine Reviews J. Clin. End. & Metab.
Molecular Endocrinology Recent Prog. Horm. Res. All Endocrine Journals
Copyright © 1975 by The Endocrine Society