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T₃ Thyrotoxicosis Due to Metastatic Thyroid Carcinoma

Nuclear Medicine Service, Veterans Administration Hospital, and the Departments of Medicine and Radiology, University of California San Francisco Medical Center San Francisco, California

¹ Reprint Requests: Nuclear Medicine Service VA Hospital, 4150 Clement St., San Francisco, California 94121.

An unusual case of T₃ thyrotoxicosis clue to metastatic follicular carcinoma of the thyroid is presented. The primary tumor and normal thyroid tissue were ablated previously by thyroidectomy and large therapeutic doses of ¹³¹I iodide. Subsequent tracer studies showed no uptake of ¹³¹I in the neck. Serum levels of total and free thyroxine were normal, and the serum T₃ concentration was abnormally high at a time when no normal thyroid tissue remained and exogenous T₃ had been discontinued. Therefore, the thyrotoxicosis in this patient was most likely due to overproduction of T₃ by the metastatic tumor.

Received May 31, 1972.

This article has been cited by other articles:

				U. M. KABADI and J. ALBIN T3 Euthyroidism in Follicular Thyroid Carcinoma Ann Intern Med, March 1, 1978; 88(3): 359 - 360. [Abstract] [PDF]