Testosterone Propionate in the Treatment of Angina Pectoris
L. HAMM, M.D.
Boston, Massachusetts
EXTENSIVE EXPERIMENTATION in animals has demonstrated that thesex hormones very definitely effect certain non-sex organs oftheir bodies. Ratschow and Kosterman (1), using androgens experimentallyin rats, report an absence of sloughing following severe vasoconstrictionby ergotamine. Korenchevsky (2) and his coworkers report changesin weight and in histologic structure in rat livers and heartsfollowing administration of androsterone or testosterone estersto the animals, attributing certain hepatotrophic and cardiotrophicproperties to these hormones. That these hormones also exertnephny trophic effects was reported in an earlier paper by thesame authors. Therapeutic applicability of these propertiessuggests itself in disorders of these organs in human beingsand it is the purpose of this report to describe the resultsof such treatment in suitable cases of angina pectoris and ofangina of effort.1
The effect of testosterone on the human cardiovascular systemhas been the subject of but few reports in the literature thusfar.
Received March 24, 1942.
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