Journal of Clinical Endocrinology & Metabolism Vol. 14, No. 1 79-86 doi:10.1210/jcem-14-1-79 Copyright © 1954 by the Endocrine Society. STRUMA LYMPHOMATOSA: CLINICAL MANIFESTATIONS AND RESPONSE TO THERAPY*WALTER E. FURR, JR., M.D. and GEORGE CRILE, JR., M.D.The Department of General Surgery, Cleveland Clinic, and the Frank E. Bunts Educational Institute Cleveland, Ohio STRUMA lymphomatosa is generally considered to be a clinicopathologic entity, of which the cause remains unknown. In recent years some have considered it to be a degenerative disease, in contrast to the earlier views that it was of inflammatory origin (1, 2, 3). Until recently, a correct diagnosis was not often made preoperatively. The treatment remains in dispute. This study summarizes the clinical features of 62 cases of struma lymphomatosa studied at the Cleveland Clinic from January 1940 through December 1952, in which the diagnosis was established by thyroidectomy or needle biopsy. Dr. J. B. Hazard of the Department of Surgical Pathology reviewed the histologic material of all the cases and roughly graded each specimen as to the degree of lymphocyte infiltration, fibrosis and lymph node formation.
* Presented at the Annual Meeting of the American Goiter Association, Chicago, Ill., May 7–9, 1953. This article will be included in the bound volume of the 1953 "Transactions of the American Goiter Association," published by Charles C Thomas, Publisher, which will be available for purchase early in 1954. Received May 9, 1953. This article has been cited by other articles:
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