| Patient no. |
Age (yr)/sex |
History |
Subjective pain score out of 10 |
Prior goiter (yr) |
Thyroid gland (size estimated by palpation) |
ESR (mm/h) |
CRP (mg/dl) |
TT4 (µg/dl)/FTI |
TSH (mIU/liter) |
24-h RAIU (%) |
MCHA/TGHA titer |
FNA |
|
| 1 |
36/F |
Intermittent daily neck pain and swelling, sore throat, 5 months |
2 |
0.75 |
25 g, smooth, diffuse, firm goiter. Tender bilaterally |
11 |
1.3 |
8.3/8.8 |
1.5 |
23% |
320/160 |
ND |
| 2 |
26/F |
Known HT/hypothyroidism on L-T4 over 3 yr. Severe constant pain over goiter, 1-2 yr |
10 |
8 |
40–50 g, R > L enlarged. Exquisitely tender bilaterally |
20 |
ND |
6.9/6.1 |
9.2a |
27% |
20,480/40 |
Numerous lymphocytes with Hürthle cell change consistent with HT |
| 3 |
39/F |
Known HT/hypothyroidism on L-T4 7 yr. Episodic throat pain radiating to chin and ears, 3 yr |
10 |
9 |
Mildly enlarged. Tender L > R |
10 |
<0.3 |
12.1/ND |
1.46b |
7 yr ago, normal |
6,400/ND |
Inconclusive |
| 4 |
48/F |
Initially "like SAT" with fever, severe fatigue, and weakness 1 wk after URTI episode, followed by episodic neck pain over next 7 months |
7 |
No |
Initially enlarged. At 7 months, not enlarged, 8.5 g (USS) |
11–39 (NR 1–39) |
<0.3 |
5.9/ND |
4.6 |
Initial, 2%. At 7 months, 28% |
Initial, Negative/12.9 to 26.7 U/ml. At 7 months, 0/0 |
Florid lymphocytic thyroiditis |
| 5 |
28/F |
Known HT 10 months. Painful goiter, with pain radiating to both ears, odynophagia, 1 month |
2 |
1 |
60 g, firm, tender bilaterally |
11–17 |
ND |
5.0/5.9 |
4 |
25% |
>20,480/10,240 |
HT, occasional giant cells |
| 6 |
22/F |
On L-T4 for suppression of diffuse goiter. Pain confined to R thyroid lobe, radiating to R ear, 2 months, with dysphagia, fatigue |
9 |
4 |
40 g, R > L enlarged. Tender R lobe |
18 |
ND |
10.8/11.6 |
0.3c |
5h, 7%, 31 h, 17% (on L-T4) |
1,280/40 |
ND |
| 7 |
41/F |
Seronegative goiter with hypothyroidism 1.25 yr. Severe constant pain over thyroid, especially R side, 5 months, with odynophagia, hoarseness of voice, and undocumented fever |
10 |
1.25 |
1.5 times, R > L enlarged. Tender bilaterally |
16–22 |
1.2 (NR 0–1.8) |
11/9.6 |
0.8d |
ND |
0/0 |
HT, occasional giant cells |
Normal range
|
|
|
|
Up to 20 g |
0–20 |
<0.3 |
5–12/6–10 |
0.3–3.8 |
10–30% |
0 /0 |
|